C₁₂H₁₆N₂O₂ with Versatile Pharmacophore​

Methyl 4-(1-piperazinyl)benzoate​ CAS 163210-97-7​ is a synthetic organic compound belonging to the class of piperazine-containing benzoate esters. It consists of a benzoate ester core (methyl para-aminobenzoate derivative) where the amino group is part of a piperazine ring. This structure makes it a versatile pharmacophore​ and key synthetic intermediate.Methyl 4-(1-piperazinyl)benzoate is a privileged pharmaceutical building block​ that combines a synthetically versatile benzoate ester with a piperazine ring—a ubiquitous pharmacophore in CNS-active drugs. Its primary advantage lies in being the definitive, high-value intermediate​ in the synthesis of blockbuster antipsychotics, while also serving as a versatile scaffold for novel drug discovery.