Pharmaceutical Intermediates C₁₀H₁₃NO₃

4-tert-Butyl-2-nitrophenol​ CAS 3279-07-0 is an organic compound belonging to the class of nitrophenols. It features a phenol ring substituted with a strong electron-donating tert-butyl group at the para position and a strong electron-withdrawing nitro group ortho to the hydroxyl group. This combination of substituents creates unique electronic and steric properties.4-tert-Butyl-2-nitrophenol is a strategically substituted phenolic building block​ whose unique structure—combining a sterically bulky electron-donating group with an ortho-positioned electron-withdrawing nitro group—makes it an indispensable precursor for high-performance, sterically hindered stabilizers and dyes. Its specific substitution pattern enables precise molecular architectures unattainable with simpler phenols.